Researches have been made showing the relative physical safety of DMT. Ayahuasca, the DMT-containing brew from the Amazon, has been studied by multidisciplinary groups in Brazil and other countries and was shown that in reasonable doses in a careful context, it presents no negative cognitive/psychiatric/physical consequences.There is yet little research into vaporized DMT, but there seems to be no sign that it is in any way more dangerous physically than other administration forms. There are no reported deaths from smoking DMT. Smoking it will not lead to a dangerous overdose because the onset is so quick that one can only inhale a certain (pharmacologicaly safe)amount before being gone to ´hyperspace', without being able to smoke more until one is down again.However:
BE IN A PHYSICALLY SAFE ENVIRONMENT!, and remember to never trip above ground level.
- Somatic effects such as possibility of increased heart-rate means people with dangerous heart or other life-threatening conditions are contra-indicated, and should NOT use DMT unless they have consulted a qualified health professional about it.
- Also, it is possible that during the experience, one temporarily loses orientation in the consensus reality, so smoking/ingesting next to a cliff, sharp objects, etc, is not a good idea.
- DO NOT use MAOIs (so for example an ayahuasca brew) together with stimulants (like mdma/amphetamines) or SSRI medication (like prozac), this can cause serotonin syndrome and lead to convulsions or even death!
The research mentioned above has shown that in a careful controlled setting, ayahuasca (oral DMT) use, even with a certain regularity, causes no cognitive/emotional/social problems. Users presented elevated levels of happiness and health. Nevertheless, these users were part of a strong-knit community with shared values and constant support between the members. The controlled setting they partook the substance in helped them make sense of the experience and special care has been taken in integration (see Integration section below).Vaporized DMT, on the other hand, has not been the focus of published studies. The overwhelmingly extreme nature of the experience, as well as the almost instantaneous onset (wherein the user is launched into the peak experience within a minute or less) lends itself to the possibilities of panic and existential terror. The complete and utter inscrutability of the experience can leave one vulnerable in the aftermath. As mentioned above, integration issues big and small are not at all uncommon. Most who have traveled to any degree have dealt with this in some way. It is very important that those planing on vaporizing DMT take a special care with set and setting, approach with a respectful attitude and take time for integrating experiences.Like with other psychedelics, DMT provides a very powerful emotional/mental experience, so those with personal or family psychiatric history are contra-indicated. A psychedelic experience can possibly waken a latent schizophrenia or exarcebate a pre-existing mental illness.While there are several cases of 'psychological healing' and anecdotal reports of cured depressions and other mental issues, DMT and other psychedelics should not be considered a cure-all and will not heal everybody. People who are unstable emotionally or going through some very difficult moments in life should be aware of the special risks that undertaking this experience has for them. If, after informing themselves thoroughly of the possible risks, they still decide to do it, then it's recommended to do it only under the supervision of an experienced person/professional/shaman, as well as taking special good care with set and setting and integration.There has been at least one case witnessed in this forum where a member appeared to suffer from a mental-breakdown following DMT usage. Most people who are drawn to DMT have a history of use with other substances that could potentially have had negative impacts on mental health. Some may be bringing existing problems with them- we are not aware of the mental health history of members. For these reasons, it is unclear whether isolated instances of mental health problems are due to DMT usage.If you feel that your mental health may not be in tip-top condition, and even if it is, research very carefully before deciding if you want to commit to this path.